Mercapto PEG Derivatives
This linear PEG derivative has a sulfhydryl group (-SH) on one chain end. The free thiol groups react readily with maleimido or iodacetamido functionalities or transition metal surfaces like gold, silver etc. Reaction with other free thiols leads to S-S disulfide bonds which can be cleaved by reducing agents. PEG thiols may also be conjugated by thiol-ene chemistry.
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