4-(Hydroxymethyl) Benzoic Acid (HMBA) on HypoGel® Resins

HypoGel® is a hydrophilic gel type resin which combines high capacities with good solvent compatibility. Glycol spacers with n = 5 or 10 EO units separate the reactive sites from the polystyrene matrix and modify the hydrophobic properties of the polystyrene backbone. Due to the spacer effect the functional group shows a higher mobility which results in higher kinetic rates and high resolution NMR spectra from immobilized compounds on the bead. The resin is compatible to a wide range of solvents and in contrast to polystyrene even polar solvents like methanol or ethanol can be used.

These resins show high loading and a hydrophilicity between polystyrene and TentaGel®

This resin is derived from HypoGel® amine and the base labile 4-(hydroxymethyl)benzoic acid linker. It is a versatile support for the immobilization of carboxylic acids. The resulting ester bond is stable to strong acids but is cleaved by nucleophiles like amines, hydrazine or alkoxides.


L 17

price: 145


HypoGel® 200 HMBA

n = 5
particle size: 110 - 150 µm
capacity: 0.6 - 0.8 mmol/g

price: 145


HypoGel® 400 HMBA

n = 10
particle size: 110 - 150 µm
capacity: 0.4 - 0.6 mmol/g

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