Polystyrene AM NH₂

Product information

Aminomethylated polystyrene resins are prepared in-house from crosslinked polystyrenes by a direct aminomethylation reaction and are chemically defined, homogeneous and free from any additional crosslinking by the functionalization process. Aminomethylated polystyrene resins can easily be acylated with any appropriate carboxylic acid-containing linker using standard methods to generate supports for solid phase organic synthesis.


Literature

L 34 Aminomethyl Polystyrene Resins

  1. Mitchell, A. R.; Kent, S. B. H.; Engelhard, M.; Merrifield, R. B. A New Synthetic Route to Tert-Butyloxycarbonylaminoacyl-4-(Oxymethyl)Phenylacetamidomethyl-Resin, an Improved Support for Solid-Phase Peptide Synthesis. J. Org. Chem. 1978, 43 (14), 2845-2852. doi: 10.1021/jo00408a022.
  2. Kornreich, W.; Anderson, H.; Porter, J.; Vale, W.; Rivier, J. Peptide N-Alkylamides by Solid Phase Synthesis. Int. J. Pept. Protein Res. 1985, 25 (4), 414-420. doi: 10.1111/j.1399-3011.1985.tb02194.x.
  3. Cardno, M.; Bradley, M. A Simple Multiple Release System for Combinatorial Library and Peptide Analysis. Tetrahedron Lett. 1996, 37 (1), 135-138. doi: 10.1016/0040-4039(95)02092-6.