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ScavengePore Phenethyldiethylamine

Product information

Polymer bound scavengers are important tools for removal of excess reagents or side products in solution phase combinatorial chemistry. ScavengePore is based on a macroporous high crosslinked polystyrene/DVB resin matrix. The permanent porosity provides a broad range of solvent compatibility. The pore size is in the range of 30 - 50 nm.
In contrast to standard Gel® type low crosslinked polystyrene/DVB resins swelling is significantly reduced. A particle size of 200 - 400 µm allows easy filtration.
Scavenger resin for protons, acids and other electrophiles. Catalyzes acylation reactions.


Literature

L 48 Scavenger Resins

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  2. Booth, R. J.; Hodges, J. C. Polymer-Supported Quenching Reagents for Parallel Purification. J. Am. Chem. Soc. 1997, 119 (21), 4882-4886. doi: 10.1021/ja9634637.
  3. Creswell, M. W.; Bolton, G. L.; Hodges, J. C.; Meppen, M. Combinatorial Synthesis of Dihydropyridone Libraries and Their Derivatives. Tetrahedron 1998, 54 (16), 3983-3998. doi: 10.1016/s0040-4020(98)00130-6.
  4. Flynn, D. L.; Crich, J. Z.; Devraj, R. V.; Hockerman, S. L.; Parlow, J. J.; South, M. S.; Woodard, S. Chemical Library Purification Strategies Based on Principles of Complementary Molecular Reactivity and Molecular Recognition. J. Am. Chem. Soc. 1997, 119 (21), 4874-4881. doi: 10.1021/ja963462e.
  5. Lawrence, R. M.; Biller, S. A.; Fryszman, O. M.; Poss, M. A. Automated Synthesis and Purification of Amides: Exploitation of Automated Solid Phase Extraction in Organic Synthesis. Synthesis (Mass.) 1997, 1997 (05), 553-558. doi: 10.1055/s-1997-1232.
  6. Suto, M. J.; Gayo-Fung, L. M.; Palanki, M. S. S.; Sullivan, R. Solution-Phase Parallel Synthesis Using Ion-Exchange Resins. Tetrahedron 1998, 54 (16), 4141-4150. doi: 10.1016/s0040-4020(98)00141-0.