€ 46,00*
SIZE
200 - 400 µm
Capacity
0.5 - 2.5 mmol/g
Product number
SC11013.5G
SC11013.5G
Product information
Polymer bound scavengers are important tools for removal of excess reagents or side products in solution phase combinatorial chemistry. ScavengePore is based on a macroporous high crosslinked polystyrene/DVB resin matrix. The permanent porosity provides a broad range of solvent compatibility. The pore size is in the range of 30 - 50 nm.
In contrast to standard Gel® type low crosslinked polystyrene/DVB resins swelling is significantly reduced. A particle size of 200 - 400 µm allows easy filtration.
Polymer bound weak acid. Scavenger resin for amines and other basic compounds, weak acid ion exchanger.
Literature
L 48 Scavenger Resins
- Kaldor, S. W.; Siegel, M. G.; Fritz, J. E.; Dressman, B. A.; Hahn, P. J. Use of Solid Supported Nucleophiles and Electrophiles for the Purification of Non-Peptide Small Molecule Libraries. Tetrahedron Lett. 1996, 37 (40), 7193-7196. doi: 10.1016/0040-4039(96)01636-x.
- Booth, R. J.; Hodges, J. C. Polymer-Supported Quenching Reagents for Parallel Purification. J. Am. Chem. Soc. 1997, 119 (21), 4882-4886. doi: 10.1021/ja9634637.
- Creswell, M. W.; Bolton, G. L.; Hodges, J. C.; Meppen, M. Combinatorial Synthesis of Dihydropyridone Libraries and Their Derivatives. Tetrahedron 1998, 54 (16), 3983-3998. doi: 10.1016/s0040-4020(98)00130-6.
- Flynn, D. L.; Crich, J. Z.; Devraj, R. V.; Hockerman, S. L.; Parlow, J. J.; South, M. S.; Woodard, S. Chemical Library Purification Strategies Based on Principles of Complementary Molecular Reactivity and Molecular Recognition. J. Am. Chem. Soc. 1997, 119 (21), 4874-4881. doi: 10.1021/ja963462e.
- Lawrence, R. M.; Biller, S. A.; Fryszman, O. M.; Poss, M. A. Automated Synthesis and Purification of Amides: Exploitation of Automated Solid Phase Extraction in Organic Synthesis. Synthesis (Mass.) 1997, 1997 (05), 553-558. doi: 10.1055/s-1997-1232.
- Suto, M. J.; Gayo-Fung, L. M.; Palanki, M. S. S.; Sullivan, R. Solution-Phase Parallel Synthesis Using Ion-Exchange Resins. Tetrahedron 1998, 54 (16), 4141-4150. doi: 10.1016/s0040-4020(98)00141-0.