ɑ-Methoxy-ω-Succinamic Acid PEG

ɑ-Methoxy-ω-Carboxy PEG

€ 93,00*

SIZE

20 000 Dalton

AMOUNT

Product number
1220000-3.1G

Product information

This methoxy capped PEG carboxylic acid has a succinic acid (C4) group atteached via an amide linkage. After activation with coupling reagents (e.g. NHS, DCC) it is useful for pegylation of amine substrates (forming an amide bond) or for the formation of hydrolyzable esters and thioesters.

Literature

L 76 α-Methoxy-ω-Amido Succinic Acid PEGs

Khandhar, A. P.; Wilson, G. J.; Kaul, M. G.; Salamon, J.; Jung, C.; Krishnan, K. M. Evaluating Size-Dependent Relaxivity of PEGylated-USPIOs to Develop Gadolinium-Free T1 Contrast Agents for Vascular Imaging. J. Biomed. Mater. Res. A 2018, 106 (9), 2440-2447. doi: 10.1002/jbm.a.36438.

Li, N.; Lu, X.; Fang, M.; Qiu, Z.; Chen, X.; Ren, L.; Ouyang, P.; Chen, G. PEGylated Triacontanol Substantially Enhanced the Pharmacokinetics of Triacontanol in Rats. J. Agric. Food Chem. 2018, 66 (33), 8722-8728. doi: 10.1021/acs.jafc.8b02684.

Steiert, E.; Radi, L.; Fach, M.; Wich, P. R. Protein-Based Nanoparticles for the Delivery of Enzymes with Antibacterial Activity. Macromol. Rapid Commun. 2018, 39 (14), e1800186. doi: 10.1002/marc.201800186.

Macho-Fernandez, E.; Chekkat, N.; Ehret, C.; Thomann, J.-S.; De Giorgi, M.; Spanedda, M. V.; Bourel-Bonnet, L.; Betbeder, D.; Heurtault, B.; Faveeuw, C.; Fournel, S.; Frisch, B.; Trottein, F. Solubilization of α-Galactosylceramide in Aqueous Medium: Impact on Natural Killer T Cell Activation and Antitumor Responses. Int. J. Pharm. 2017, 530 (1-2), 354-363. doi: 10.1016/j.ijpharm.2017.07.054.

He, C.; Yang, Q.; Tan, L.; Liu, B.; Zhu, Z.; Gong, B.; Shen, Y.-M.; Shao, Z. Design and Synthesis of Redox and Oxidative Dual Responsive Block Copolymer Micelles for Intracellular Drug Delivery. Eur. Polym. J. 2016, 85, 38-52. doi: 10.1016/j.eurpolymj.2016.09.047.

Zoetebier, B.; Sohrabi, A.; Lou, B.; Hempenius, M. A.; Hennink, W. E.; Vancso, G. J. PEG Stabilized DNA - Poly(Ferrocenylsilane) Polyplexes for Gene Delivery. Chem. Commun. (Camb.) 2016, 52 (49), 7707-7710. doi: 10.1039/c6cc02733d.