€ 399,00*
SIZE
2000 Dalton
Product number
122000-44.1G
122000-44.1G
Product information
Orthopyridyl disulfide (OPSS) PEGs are thiol-specific PEGylation reagents that react with free sulfhydryls (-SH) at a wide pH range (pH 3-10) through disulfide exchange. The newly formed disulfide (S-S) bond is unstable in a reducing environment. Thus, the bond can be cleaved to reverse the pegylation and release free thiols.
Literature
L 79 α-Methoxy-ω-OPSS PEGs
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- Mahendran, K. R.; Niitsu, A.; Kong, L.; Thomson, A. R.; Sessions, R. B.; Woolfson, D. N.; Bayley, H. A Monodisperse Transmembrane α-Helical Peptide Barrel. Nat. Chem. 2017, 9 (5), 411-419. doi: 10.1038/nchem.2647.
- Wang, X.; Li, D.; Yang, F.; Shen, H.; Li, Z.; Wu, D. Controlled Cross-Linking Strategy: From Hybrid Hydrogels to Nanoparticle Macroscopic Aggregates. Polym. Chem. 2013, 4 (17), 4596. doi: 10.1039/c3py00811h