ScavengePore Phenethylmorpholine

€ 83,00*

SIZE

200 - 400 µm

Capacity

0.4 - 1.0 mmol/g

AMOUNT

Product number
SC11209.5G

Product information

Polymer bound scavengers are important tools for removal of excess reagents or side products in solution phase combinatorial chemistry. ScavengePore is based on a macroporous high crosslinked polystyrene/DVB resin matrix. The permanent porosity provides a broad range of solvent compatibility.
In contrast to standard Gel^® type low crosslinked polystyrene/DVB resins swelling is significantly reduced. A particle size of 200 - 400 µm allows easy filtration.
Scavenger resin for protons, acids and other electrophiles.

Literature

L 48 Scavenger Resins

Kaldor, S. W.; Siegel, M. G.; Fritz, J. E.; Dressman, B. A.; Hahn, P. J. Use of Solid Supported Nucleophiles and Electrophiles for the Purification of Non-Peptide Small Molecule Libraries. Tetrahedron Lett. 1996, 37 (40), 7193-7196. doi: 10.1016/0040-4039(96)01636-x.

Booth, R. J.; Hodges, J. C. Polymer-Supported Quenching Reagents for Parallel Purification. J. Am. Chem. Soc. 1997, 119 (21), 4882-4886. doi: 10.1021/ja9634637.

Creswell, M. W.; Bolton, G. L.; Hodges, J. C.; Meppen, M. Combinatorial Synthesis of Dihydropyridone Libraries and Their Derivatives. Tetrahedron 1998, 54 (16), 3983-3998. doi: 10.1016/s0040-4020(98)00130-6.

Flynn, D. L.; Crich, J. Z.; Devraj, R. V.; Hockerman, S. L.; Parlow, J. J.; South, M. S.; Woodard, S. Chemical Library Purification Strategies Based on Principles of Complementary Molecular Reactivity and Molecular Recognition. J. Am. Chem. Soc. 1997, 119 (21), 4874-4881. doi: 10.1021/ja963462e.

Lawrence, R. M.; Biller, S. A.; Fryszman, O. M.; Poss, M. A. Automated Synthesis and Purification of Amides: Exploitation of Automated Solid Phase Extraction in Organic Synthesis. Synthesis (Mass.) 1997, 1997 (05), 553-558. doi: 10.1055/s-1997-1232.

Suto, M. J.; Gayo-Fung, L. M.; Palanki, M. S. S.; Sullivan, R. Solution-Phase Parallel Synthesis Using Ion-Exchange Resins. Tetrahedron 1998, 54 (16), 4141-4150. doi: 10.1016/s0040-4020(98)00141-0.