€ 152,00*
SIZE
250 - 315 µm
Capacity
0.5 - 1.1 mmol/g
Product number
HA25031507.5G
HA25031507.5G
Product information
For Boc solid phase synthesis of N-alkyl amides by reductive amination as well as for the synthesis of sulfonamides, anilides and amines, respectively. The phenethylether linkage is more stable than the acid-sensitive benzylic bond in the Wang analogous benzaldehyde resins.
Literature
L 30 4-Formyl-phenoxyethyl Polystyrene Resins (4-Alkoxybenzaldehyde Resin)
- Bourne, G. T.; Meutermans, W. D. F.; Alewood, P. F.; McGeary, R. P.; Scanlon, M.; Watson, A. A.; Smythe, M. L. A Backbone Linker for BOC-Based Peptide Synthesis and on-Resin Cyclization: Synthesis of Stylostatin 1. J. Org. Chem. 1999, 64 (9), 3095-3101. doi: 10.1021/jo9818780.
- Raju, B.; Kogan, T. P. Use of Halomethyl Resins to Immobilize Amines: An Efficient Method for Synthesis of Sulfonamides and Amides on a Solid Support. Tetrahedron Lett. 1997, 38 (28), 4965-4968. doi: 10.1016/s0040-4039(97)01076-9.
- Miller, M. W.; Vice, S. F.; McCombie, S. W. Mild N-Dealkylation of Tertiary, Benzylic Amines with Acid Chlorides: Application to Solid-Phase Chemistry. Tetrahedron Lett. 1998, 39 (21), 3429-3432. doi: 10.1016/s0040-4039(98)00584-x.
- Kobayashi, S.; Aoki, Y. P-Benzyloxybenzylamine (BOBA) Resin. A New Polymer-Supported Amine Used in Solid-Phase Organic Synthesis. Tetrahedron Lett. 1998, 39 (40), 7345-7348. doi: 10.1016/s0040-4039(98)01576-7.
- Boojamra, C. G.; Burow, K. M.; Ellman, J. A. An Expedient and High-Yielding Method for the Solid-Phase Synthesis of Diverse 1,4-Benzodiazepine-2,5-Diones. J. Org. Chem. 1995, 60 (18), 5742-5743. doi: 10.1021/jo00123a001.