Polystyrene A FMP

Product information

The lack of amide bonds and of benzylic linkages makes this resin ideal for solid phase synthesis of secondary sulfonamides and carboxamides as well as of N-alkyl peptide amides.


Literature

L 31 4-Formyl-3-methoxy-phenoxyethyl Polystyrene Resins (2-Methoxy-4-alkoxybenzaldehyde Resin)

  1. Fivush, A. M.; Willson, T. M. AMEBA: An Acid Sensitive Aldehyde Resin for Solid Phase Synthesis. Tetrahedron Lett. 1997, 38 (41), 7151-7154. doi: 10.1016/s0040-4039(97)01771-1.
  2. Sarantakis, D.; Bicksler, J. J. Solid Phase Synthesis of Sec-Amides and Removal from the Polymeric Support under Mild Conditions. Tetrahedron Lett. 1997, 38 (42), 7325-7328. doi: 10.1016/s0040-4039(97)01779-6.
  3. Dörner , B.; et al. Preparation of Carboxy-Modified Peptide Fragments using Alkyoxybenzaldehyde Resins in Peptides 1998 Proceedings of the Twenty-Fifth European Peptide Symposium, 1998 Budapest, Hungary; (Bajusz, S.; Hudesz, F, Eds.); Akadémiai K: Budapest, Hungary, 1999, 90. ISBN: 9630576228
  4. Mazurov, A. Traceless Synthesis of Benzimidazoles on Solid Support. Bioorg. Med. Chem. Lett. 2000, 10 (1), 67-70. doi: 10.1016/s0960-894x(99)00592-2.
  5. Swayze, E. E. Secondary Amide-Based Linkers for Solid Phase Organic Synthesis. Tetrahedron Lett. 1997, 38 (49), 8465-8468. doi: 10.1016/s0040-4039(97)10281-7.
  6. Bilodeau, M. T.; Cunningham, A. M. Solid-Supported Synthesis of Imidazoles: A Strategy for Direct Resin-Attachment to the Imidazole Core. J. Org. Chem. 1998, 63 (9), 2800-2801. doi: 10.1021/jo980027p.
  7. Farrant, E.; Rahman, S. S. A Solid-Phase Synthetic Route to Substituted 7-Azabenzimidazoles Suitable for Combinatorial Library Synthesis. Tetrahedron Lett. 2000, 41 (28), 5383-5386. doi: 10.1016/s0040-4039(00)00859-5.
  8. Caddick, S.; Hamza, D.; Wadman, S. N. Solid-Phase Intermolecular Radical Reactions 1. Sulfonyl Radical Addition to Isolated Alkenes and Alkynes. Tetrahedron Lett. 1999, 40 (40), 7285-7288. doi: 10.1016/s0040-4039(99)01525-7.