Wang resins are the standard supports for the synthesis of peptide acids by solid phase synthesis using the Fmoc strategy.We have now expanded the family of low-loaded Wang resins to include the amino acid Fmoc-Lys(Mtt) Wang Resin LL.
Fmoc protected amino acids are linked to Polystyrene-PHB (Wang resin, consisting of 1% crosslinked polystyrene functionalized with the TFA labile p-benzyloxybenzyl alcohol linker).
50 - 95% TFA treatment generates free peptide acids.
Low loaded Fmoc AA Wang resin - an ideal support for the synthesis of long or difficult peptides.
Capacity: 0.2 - 0.35 mmol/g
Enantiomeric purity*: > 99.5%
Dipeptide content: < 0.5%
*with exception of Cys and His
Fmoc D-amino acids on request.
Fmoc protected amino acids are linked to Polystyrene-PHB (Wang resin, consisting of 1% crosslinked polystyrene functionalized with the TFA labile p-benzyloxybenzyl alcohol linker).
50 - 95% TFA treatment generates free peptide acids.
Low loaded Fmoc AA Wang resin - an ideal support for the synthesis of long or difficult peptides.
Capacity: 0.2 - 0.35 mmol/g
Enantiomeric purity*: > 99.5%
Dipeptide content: < 0.5%
*with exception of Cys and His
Fmoc D-amino acids on request.
Figure 1: Fmoc-Lys(Mtt) Wang Resin LL.