Polystyrene Sulfonic Acid

Product information

This polymer support is an equivalent to p-toluene sulfonic acid and can be used instead of soluble organic acids for quenching or catalysis of reactions. It can be also used for scavenging and "catch and release" applications.


Literature

L 48 Scavenger Resins

  1. Kaldor, S. W.; Siegel, M. G.; Fritz, J. E.; Dressman, B. A.; Hahn, P. J. Use of Solid Supported Nucleophiles and Electrophiles for the Purification of Non-Peptide Small Molecule Libraries. Tetrahedron Lett. 1996, 37 (40), 7193-7196. doi: 10.1016/0040-4039(96)01636-x.
  2. Booth, R. J.; Hodges, J. C. Polymer-Supported Quenching Reagents for Parallel Purification. J. Am. Chem. Soc. 1997, 119 (21), 4882-4886. doi: 10.1021/ja9634637.
  3. Creswell, M. W.; Bolton, G. L.; Hodges, J. C.; Meppen, M. Combinatorial Synthesis of Dihydropyridone Libraries and Their Derivatives. Tetrahedron 1998, 54 (16), 3983-3998. doi: 10.1016/s0040-4020(98)00130-6.
  4. Flynn, D. L.; Crich, J. Z.; Devraj, R. V.; Hockerman, S. L.; Parlow, J. J.; South, M. S.; Woodard, S. Chemical Library Purification Strategies Based on Principles of Complementary Molecular Reactivity and Molecular Recognition. J. Am. Chem. Soc. 1997, 119 (21), 4874-4881. doi: 10.1021/ja963462e.
  5. Lawrence, R. M.; Biller, S. A.; Fryszman, O. M.; Poss, M. A. Automated Synthesis and Purification of Amides: Exploitation of Automated Solid Phase Extraction in Organic Synthesis. Synthesis (Mass.) 1997, 1997 (05), 553-558. doi: 10.1055/s-1997-1232.
  6. Suto, M. J.; Gayo-Fung, L. M.; Palanki, M. S. S.; Sullivan, R. Solution-Phase Parallel Synthesis Using Ion-Exchange Resins. Tetrahedron 1998, 54 (16), 4141-4150. doi: 10.1016/s0040-4020(98)00141-0.

L 51 Sulphonic Acid Resins

  1. Flynn, D. L.; Crich, J. Z.; Devraj, R. V.; Hockerman, S. L.; Parlow, J. J.; South, M. S.; Woodard, S. Chemical Library Purification Strategies Based on Principles of Complementary Molecular Reactivity and Molecular Recognition. J. Am. Chem. Soc. 1997, 119 (21), 4874-4881. doi: 10.1021/ja963462e.
  2. Gayo, L. M.; Suto, M. J. Ion-Exchange Resins for Solution Phase Parallel Synthesis of Chemical Libraries. Tetrahedron Lett. 1997, 38 (4), 513-516. doi: 10.1016/s0040-4039(96)02362-3.
  3. Siegel, M. G.; Hahn, P. J.; Dressman, B. A.; Fritz, J. E.; Grunwell, J. R.; Kaldor, S. W. Rapid Purification of Small Molecule Libraries by Ion Exchange Chromatography. Tetrahedron Lett. 1997, 38 (19), 3357-3360. doi: 10.1016/s0040-4039(97)00650-3.
  4. Shuker, A. J.; Siegel, M. G.; Matthews, D. P.; Weigel, L. O. The Application of High-Throughput Synthesis and Purification to the Preparation of Ethanolamines. Tetrahedron Lett. 1997, 38 (35), 6149-6152. doi: 10.1016/s0040-4039(97)01421-4.
  5. Lawrence, R. M.; Biller, S. A.; Fryszman, O. M.; Poss, M. A. Automated Synthesis and Purification of Amides: Exploitation of Automated Solid Phase Extraction in Organic Synthesis. Synthesis (Mass.) 1997, 1997 (05), 553-558. doi: 10.1055/s-1997-1232.
  6. Parlow, J. J.; Flynn, D. L. Solution-Phase Parallel Synthesis of a Benzoxazinone Library Using Complementary Molecular Reactivity and Molecular Recognition (CMR/R) Purification Technology. Tetrahedron 1998, 54 (16), 4013-4031. doi: 10.1016/s0040-4020(98)00132-x.