Weinreb Amide Linker

05/02/2024

The Weinreb Amide (N-Methoxy-ß-alanine) Linker attached to aminomethylated polystyrene. This support is suited for the synthesis of peptide aldehydes or ketones. Cleavage is accomplished by treatment with LiAlH4 or Grignard reagents, respectively.

Figure 1: Weinreb Amide (N-Methoxy-ß-alanine) Linker on PS AM.