L 47

HypoGel® is a hydrophilic gel type resin which combines high capacities with good solvent compatibility. Glycol spacers with n = 5 or 10 EO units separate the reactive sites from the polystyrene matrix and modify the hydrophobic properties of the polystyrene backbone. Due to the spacer effect the functional group shows a higher mobility which results in higher kinetic rates and high resolution NMR spectra from immobilized compounds on the bead. The resin is compatible to a wide range of solvents and in contrast to polystyrene even polar solvents like methanol or ethanol can be used.

These resins show high loading and a hydrophilicity between polystyrene and TentaGel®

L 17

Reaction with primary amines generates immobilized N-substituted glycinal acetals suitable for the synthesis of heterocycles derived from 1-acyl-3-oxopiperazine.