
Trifunctional Hybrid Resins for Sequential Cleavage of Peptide Amides
The resins contain 5-10% non cleavable covalently attached ligands, 40 - 45% linker for peptide amide release at low concentrated TFA (5%) and 40 - 45% linker for peptide amide release with 95% TFA.
The peptide, liberated by 5% TFA treatment must be seperated from the resin and deprotected with 95% TFA in a follow up step.
This resin type is designed for screening of peptide amide libraries by sequential release.