Literature

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L 1 Review Articles

1. Synthesis of Peptides and Peptidomimetics, Houben Weyl, Eds. M. Goodman, A. Felix, L. Moroder, C. Toniolo, Georg Thieme Verlag Stuttgart, New York, (2002) Volume 22.

2. G. B. Fields, L. R. Noble, Int. J. Peptide Protein Res., (1990) 35, 161.

3. D. Hudson, J. Comb. Chem., (1999) 1, 333.

4. D. Hudson, J. Comb. Chem., (1999) 1, 403.

5. M. Lebl, J. Comb. Chem., (1999) 1, 3.

6. H. H. P. Hermkens, H. C. J. Ottenheijm, D Rees, Tetrahedron, (1996) 52, 4527.

7. H. H. P. Hermkens, H. C. J. Ottenheijm, D Rees, Tetrahedron, (1997) 53, 5643.

8. S. Booth, H. H. P. Hermkens, H. C. J. Ottenheijm, D. Rees, Tetrahedron, (1998) 54, 15385.

9. R. C. D. Brown, J. Chem. Soc., Perkin Trans., (1998) 1, 3293.

L 2 Bead Homogeneity

10. W. Rapp in Innovations and Perspectives in Solid Phase Synthesis & Combinatorial Libraries, Collected Papers of the 7th International Symposium 2001, (R. Epton, Ed.), Mayflower Worldwide Limited, Kingswinford, England, (2002), 197

11. W. Rapp, H. Fritz, E. Bayer, in Peptides, Chemistry and Biology, Proceedings of the Twelfth American Peptide Symposium, (J. A. Smith, J. E. Rivier, Eds.), ESCOM: Leiden, (1995), 275.

12. M. Eggenweiler, N. Clausen, H. Fritz, L. Zhang, E. Bayer, in Peptides 1994, Proceedings of the 23rd European Peptide Symposium, (H. L. S. Maya, Ed.), ESCOM, Leiden (1995), 87.

L 3 Macro Beads

13. W. Rapp, in Combinatorial Chemistry, Synthesis and Application, (S. R. Wilson, A. W. Czarnik, Eds.), John Wiley & Sons, Inc., (1997), 65.

14. M. Pursch, G. Schlotterbeck, L. H. Tseng, K. Albert, W. Rapp, Angew. Chem. Int. Ed. Engl., (1996) 35, 2867

15. W. Rapp, G. Nicholson, M. Maier, G. Schlotterbeck, M. Pursch, K. Albert in Innovations and Perspectives in Solid Phase Synthesis, & Combinatorial Libraries, Proceedings of the 4th International Symposium 1993, (R. Epton, Ed.), Mayflower Scientific Limited, Birmingham, (1996), 97

L 4 TentaGel® Overview

16. E. Bayer, W. Rapp in Chemistry of Peptides and Proteins, (W. Voelter, E. Bayer, Y. A. Ovchinnikov, V.T. Ivanov, Eds.) Walter de Gruyter & Co., Berlin. New York, (1986), 3.

17. E. Bayer, W. Rapp, Dtsch. Offen. DE 3,500,180, 10. Juli 1986, Anm. 4. Jan 1985, C.A. 106, 50859.

18. E. Bayer, Angew. Chem. Int. Ed. Engl., (1991) 30, 113.

19. E. Bayer, W. Rapp in Poly(Ethylene Glycol) Chemistry: Biotechnical and Biomedical Application, (M. Harris, Ed.) Plenum Press New York, (1992), 325.

20. E. Bayer, W. Rapp, German Pat. DOS 3714258, 1988.

21. E. Bayer, M. Dengler, B. Hemmasi, Int. J. Pept. Protein Res., (1985) 25, 178.

22. E. Bayer, H. Hellstern, H. Eckstein, Z. Naturforsch., (1987) 42c., 455.

23. W. Rapp, L. Zhang, R. Häbich, E. Bayer in Peptides 1988, Proceedings of the 20th European Peptide Symposium (G. Jung, E. Bayer, Eds.), Walter de Gruyter, Berlin, (1989), 1989.

24. L. Zhang, W. Rapp, E. Bayer in Peptides 1992 (C. H. Schneider, A. N. Eberle, Eds.), Proceedings of the 22nd European Peptide Symposium, Escom Leiden, (1993), 432.

25. W. Karnbrock, M. Deeg, J. Gerhardt, W. Rapp, Molecular Diversity, (1998) 4, 165.

L 5 TentaGel® Kinetics

26. E. Bayer, K. Albert, H. Willisch, W. Rapp, B. Hemmasi, Macromolecules, (1990) 23, 1937.

27. J. Rudinger, P. Buetzer in "Peptides 1974" (ed. J.Wolman), Wiley, New York, (1975), 211.

28. E. Bayer, W. Rapp in Poly(Ethylene Glycol) Chemistry: Biotechnical and Biomedical Application, (M. Harris, Ed.) Plenum Press, New York, (1992), 325.

29. L. Zhang, W. Rapp, E. Bayer in Peptides 1990, Proceedings of the 21st European Peptide Symposium (E. Giralt, D. Andreus, Eds.) Escom Leiden , (1991), 196.

30. W. Rapp in Peptides 1992, Proceedings of the 22th European Peptide Symposium (C. H. Schneider, A. N. Eberle, Eds.) Escom Leiden , (1993), 243.

31. M. Shemiakin, Y. A. Ovchinnikov, A. A. Kiryushkin, J. V. Kozhevnikova, Tetrahedron Lett., (1995) 27, 2323.

32. R. H. Andreatta, H. Rink, Helv. Chim. Acta, (1973) 65, 1205.

L 6 TentaGel® Compatibility Water / org. Solvents

33. W. Rapp, L. Zhang, W. Bannwarth, E. Bayer in Peptides 1992, Proceedings of the 22th European Peptide Symposium, Escom Leiden, (1993), 347.

L 7 TentaGel® and NMR spectroscopy

34. G. C. Look, C. P. Holmes, J. P. Chinn, M. A. Gallap, J. Org. Chem. (1994) 59, 7588.

35. W. L. Fitch, G. Detre, C. P. Holmes, J. Org. Chem. (1994) 59, 7955.

36. P. A. Keifer, J. Org. Chem., (1996) 61, 1558.

37. M. Pursch, G. Schlotterbeck, L. H. Tseng, K. Albert, W. Rapp, Angew. Chem. Int. Ed. Engl.(1996) 35, 2867

38. W. Rapp, G. Nicholson, M. Maier, G. Schlotterbeck, M. Pursch, K. Albert in Innovations and Perspectives in Solid Phase Synthesis, & Combinatorial Libraries, Proceedings of the 4th International Symposium 1993, (R. Epton, Ed.), Mayflower Scientific Limited, Birmingham, (1996), 97.

L 8 TentaGel® OH Resins

39. W. Rapp et al., in Innovation & Perspectives in Solid Phase Synthesis, 1st International Symposium, (R. Epton Ed.), SPCC UK Ltd., Birmingham, (1990), 205.

40. L. Zhang et al., in Peptides 1990, Proc. 21st European Peptide Symposium, (E. Giralt & D. Andreu Ed.), ESCOM, Leiden, (1990), 196.

41. E. Bayer, Angew. Chem. Int. Ed. Engl., (1991) 30, 113.

42. M. Hiroshige et al., Tetrahedron Lett., (1995) 36, 4567.

43. V. Krchñàk et al., Tetrahedron Lett., (1995) 36, 6193.

44. M. Patek et al., Tetrahedron Lett., (1995) 36, 2227.

45. D. Fancelli et al., Tetrahedron Lett., (1997) 38, 2311.

L 9 TentaGel® Br Resins

46. W. Rapp et al., in Innovation & Perspectives in Solid Phase Synthesis, 1st Inter-national Symposium, (R. Epton Ed.), SPCC UK Ltd, Birmingham, (1990), 205.

47. L. Zhang et al., in Peptides 1990, Proc. 21st European Peptide Symposium, (E. Giralt & D. Andreu, Eds.), ESCOM, Leiden, (1990), 196.

48. E. Bayer, Angew. Chem. Int. Ed. Engl., (1991) 30, 113.

L 10 TentaGel® NH2 Resins

49. W. Rapp et al., in Innovation & Perspectives in Solid Phase Synthesis, 1st International Symposium, (R. Epton, Ed.), SPCC UK Ltd. Birmingham, (1990), 205.

50. L. Zhang et al., in Peptides 1990, Proc. 21st European Peptide Symposium, (E. Giralt & D. Andreu, Eds.), ESCOM, Leiden, (1990), 196.

51. E. Bayer, Angew. Chem. Int. Ed. Engl., (1991) 30, 113.

52. M. Govravaram, M. A. Gallop, Tetrahedron Lett., (1997) 38, 6973.

L 11 TentaGel® COOH Resins

53. W. Rapp et al., in Innovation & Perspectives in Solid Phase Synthesis, 1st International Symposium, (R. Epton, Ed.), SPCC UK Ltd., Birmingham, (1990), 205.

54. L. Zhang et al., in Peptides 1990, Proc. 21st European Peptide Symposium, (E. Geralt & D. Andreu, Eds.), ESCOM, Leiden, (1990), 196.

55. E. Bayer, Angew. Chem. Int. Ed. Engl., (1991) 30, 113.

56. Routledge et al., Synlett., (1997), 61.

L 12 Monosized TentaGel® Resins

57. W. Rapp, E. Bayer in Innovations and Perspectives in Solid Phase Synthesis, Peptides, Polypeptides and Oligonucleotides, (R. Epton Ed.) Intercept Ltd., Andover (1992), 259.

58. W. Rapp, H. Fritz, E. Bayer in Peptides, Chemistry and Biology, (J. A. Smith, J. E. Rivier, Eds.), Proceedings of the Twelfth American Peptide Symposium, Escom, Leiden, (1992), 529.

59. E. Bayer, C. Goldammer, in Peptides, Chemistry and Biology, (J. A. Smith, J. E. Rivier, Eds.), Proceedings of the Twelfth American Peptide Symposium, Escom, Leiden, (1992), 589.

60. W. Rapp, E. Bayer, in Peptides 1992, (C. H. Schneider, A. N. Eberle, Eds.) Proceedings of the 22nd European Peptide Symposium, Escom, Leiden, (1993), 25.

61. W. Rapp, E. Bayer, in Peptide Chemistry 1992, (N. Yanahara, Ed.), Proceedings of the 2nd Japan Symposium on Peptide Chemistry, Escom, Leiden, (1993), 7.

62. W. Rapp, E. Bayer, in Peptides, Chemistry and Biology, (J. A. Smith, R. S. Hodges, Eds.), Proceedings of the Thirteenth American Peptide Symposium, Escom, Leiden, (1994), 40.

63. R. Lotz, L. Zhang, A. Korn, F. Zühl, G. Boheim, E. Bayer, G. Jung, J. Pept. Sci., (1996), submitted.

L 13 Multifunctional Resins

64. W. Rapp, L. Zhang, C. Müller. F. Zühl, K.H. Wiesmüller, G. Jung, E. Bayer, in Innovations and Perspectives in Solid Phase Synthesis, Peptides, Proteins and Nucleic Acids, Proceedings of the 3rd International Symposium 1993, (R. Epton, Ed.), Mayflower Worldwide Limited, Birmingham, (1994), 197.

65. W. Rapp, M. Maier, G. Schlotterbeck, M. Pursch, K. Albert, E. Bayer, in Peptides, Chemistry and Biology, Proceedings of the 14th American Peptide Symposium, (P. T. P. Kaumaya, R. S. Hodges, Eds.), Columbus, Ohio (1995).

66. W. Rapp, G. Nicholson, M. Maier, G. Schlotterbeck, M. Pursch, K. Albert, in Innovations and Perspectives in Solid Phase Synthesis, & Combinatorial Libraries, Proceedings of the 4th International Symposium 1993, (R. Epton, Ed.), Mayflower Scientific Limited, Birmingham, (1996), 97

L 14 TentaGel® Trt-OH Resins

67. E. Bayer, Angew. Chem. Int. Ed. Engl., (1991) 30, 113.

68. L. M. Gayo, M. J. Suto, Tetrahedron Lett., (1997) 38, 211.

69. E. Bayer et al., in Peptides Chemisty, Structure & Biology, Proc. 13th American Peptide Symposium, (R. S. Hodges, J. A. Smith, Eds.), ESCOM, Leiden, (1994), 156.

70. J. M. J. Frechet et al., Tetrahedron Lett., (1975), 3055.

71. T. M. Fyles, C. C. Leznoff, Can. J. Chem., (1976) 54, 935.

72. V. Vliet et al., in Innovation & Perspectives in Solid Phase Synthesis, 2nd International Symposium, (R. Epton, Ed.), Intercept UK Ltd., Andover, (1992), 475.

73. V. Vliet et al., in Peptides 1992, Proc. 22nd European Peptide Symposium, (C. H. Schneider, A. N. Eberle, Eds.), ESCOM, Leiden, (1993), 279.

74. G. Grübler et al., in Innovation & Perspectives in Solid Phase Synthesis, 3rd International Symposium, (R. Epton, Ed.), Mayflower Worldwide Ltd., Birmingham, (1994), 517.

75. R. Bollhagen et al., J. Chem. Soc., Chem. Commun., (1994), 2559.

76. V. Krchñák, A. S. Weichsel, Tetrahedron Lett, (1997) 38, 7299.

L 15 TentaGel® S Trt - AA Fmoc Resins

77. E. Bayer et al., in Peptides Chemisty, Structure & Biology, Proc. 13th American Peptide Symposium, (R. S. Hodges, J. A. Smith, Eds.), ESCOM, Leiden, (1994), 156.

78. G. Grübler et al., in Innovation & Perspectives in Solid Phase Synthesis, 3rd International Symposium, (R. Epton, Ed.), Mayflower Worldwide Ltd., Birmingham, (1994), 517.

L 16 TentaGel® HMB Resins

79. R. C. Sheppard et al., Int. J. Peptide Protein Res., (1982) 20, 451.

L 17 HypoGel®

80. W. Rapp, in Innovations and Perspectives in Solid Phase Synthesis & Combinatorial Libraries, Collected Papers of the 7th International Symposium 2001, (R. Epton, Ed.), Mayflower Worldwide Limited, Kingswinford, England, (2002), 197

L 18 Immunization Overview

81. S. Modrow, B. Hoflacher, R. Merz, H. Wolf, J.Immunol. Meth. (1989) 118, 1.

82. P. M. Fischer, A. Comis, M. E. Howden, J. Immunol. Meth., (1989), 118, 119.

83. M. Flegel, D. Pichova, P. Minarik, R. C. Sheppard, in Peptides 1990, Proceedings of the 21st European Peptide Symposium (E. Giralt and D. Andreu, Eds.) ESCOM, Leiden (1991), 837.

84. P. Kanda, R. C. Kennedy, J. T. Sparrow, Int. J. Pept. Protein Res., (1991), 38, 385.

85. R. C. Kennedy et al., J. Biol. Chem., (1987), 262, 5769.

86. M. Zeppezauer, R. Hoffmann, A. Schönberger, S. Rawer, W. Rapp, E. Bayer, Z. Naturforsch. (1993), 48b, 1801.

87. W. Rapp, L. Zhang, A. G. Beck-Sickinger, K. Dares, K.-H. Wiesmüller, G. Jung, E. Bayer, in Peptides 1990 Proceedings of the 21st European Peptide Symposium (E. Giralt and D. Andreu, Eds.), ESCOM, Leiden, (1991), 849.

88. S. Butz, S. Rawer, W. Rapp, U. Birsner, Pept. Res., (1994), 7, 20.

L 19 PEG peptides and Pam peptides

89. W. Rapp, L. Zhang, A. G. Beck-Sickinger, K. Dares, K.-H. Wiesmüller, G. Jung, E. Bayer, in Peptides 1990 Proceedings of the 21st European Peptide Symposium (E. Giralt and D. Andreu, Eds.), ESCOM, Leiden (1991), 849.

90. S. Butz, S. Rawer, W. Rapp, U. Birsner, Pept. Res., (1994), 7, 20.

91. T.S. Burkoth, T.L.S. Benzinger, D.N.M. Jones, K. Hallenga, S.C. Meredit, D.G. Lynn, J. Am. Chem Soc. (1998), 120, 7655-7656.

L 20 Pam3Cys, PEG Pam3Cys, PEG Pam3CysPep

92. K.-H. Wiesmüller, G. Jung, G. Hess, Vaccine , (1989), 7, 29.

93. B. Kleine, W. Rapp, K.-H. Wiesmüller, M. Edinger, W. Beck, J. Metzger, R. Ataullakhanov, G. Jung, W. G. Bessler, Immunology, (1994), 110; 53.

94. W. Rapp, L. Zhang, C. Müller. F. Zühl, K.-H. Wiesmüller, G. Jung, E. Bayer, in Innovations and Perspectives in Solid Phase Synthesis, Peptides, Proteins and Nucleic Acids, Proceedings of the 3rd International Symposium 1993, (R. Epton, Ed.), Mayflower Worldwide Limited, Birmingham, (1994), 197.

L 21 Biotinylation of peptides

95. L. Zhang, W. Rapp and E. Bayer, in Peptides 1992 (C. H. Schneider and A. N. Eberle, Eds.), Proceedings of the 22nd European Peptide Symposium, Escom Leiden, (1993), 432.

L 22 Oligonucleotides

96. R. L. Letsinger, J. L. Finnan, G. A. Heavner, W. B. Lunsford, J. Am. Chem. Soc, (1975), 97, 3278.

97. E. Uhlmann, A. Peyman, Chem. Rev., (1990), 90, 543.

98. J. W. Engels, E. Uhlmann, Angew. Chemie Int. Ed. Engl., (1989), 28, 716.

L 23 Oligonucleotide synthesis

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100. E. Bayer, K. Bleicher, M. Maier, H. J. Gaus, K. Schmeer, T. Bauer, in Solid Phase Synthesis of Peptides, Proteins, Nucleic Acids, Biological and Biomedical Applications (R. Epton, Ed.), Collected Papers, Third International Symposium, 1993, Oxford, U.K., Mayflower Worldwide Limited, Birmingham, (1994), 9.

101. G. Grübler, H. Straubinger, W. Reinig, H. Echner, M. Geiger, W. Voelter, in Solid Phase Synthesis of Peptides, Proteins, Nucleic Acids, Biological and Biomedical Applications (R. Epton, Ed.), Collected Papers, Third International Symposium, 1993, Oxford, U.K., Mayflower Worldwide Limited, Birmingham, (1994), 191.

102. H. Gao, B. L. Gaffney, R. A. Jones, Tetrahedron Lett., (1991), 32, 5477.

103. P. Wright, D. Lloyd, W. Rapp, A. Andrus, Tetrahedron Lett., (1993), 34, 3373.

104. E. Bayer, Angew. Chem., (1991), 103, 117.

105. K. Bleicher, Thesis, University of Tübingen, (1995).

106. E. Bayer , K. Bleicher, M. Maier, Z. Naturforsch, (1995), 50b, 1096.

107. J. Weiler, T. Maier, W. Pfleiderer, in Solid Phase Synthesis of Peptides, Proteins, Nucleic Acids, Biological and Biomedical Applications (R. Epton, Ed.), Collected Papers, Third International Symposium, 1993, Oxford, U.K., Mayflower Worldwide Limited, Birmingham, (1994), 131.

108. D. Tsou, P. Wright, D. Lloyd, A. Andreus, in Solid Phase Synthesis of Peptides, Proteins, Nucleic Acids, Biological and Biomedical Applications (R. Epton, Ed.), Collected Papers, Third International Symposium, 1993, Oxford, U.K., Mayflower Worldwide Limited, Birmingham, (1994), 125.

109. A. Andrus, presented at the 4th International Symposium on Solid Phase Synthesis, Edinburgh, (1995).

L 24 Library Overview

110. Furka, et al., 10th Int. Symp. Med. Chem., Budapest, (1988).

111. Furka, et al., Int. J. Pept. Prot. Rs., (1991), 37,487.

112. Furka, et al., 14th Int. Cong. of Biochem., Prague, (1988).

113. S. E. Salmon, E. M. Hersh, V. J. Hruby, W. M. Kazncierski, R. J. Knapp, Nature (1991), 354, 82.

L 25 Libraries

114. M. Lebl, V. Krchñák, N. F. Sepetov, B. Seligmann, S. Felder, Biopolymers (Peptide Sience), (J. Wiley & Sons, Eds.), (1995), 37, 177.

115. S. E. Salmon, K. S. Lam, M. Lebl, A. Kandola, P. S. Khattri, S. Wade, M. Pátek, P. Kocis, V. Krchñák, D. Thorpe, S. Felder, Proc. Natl. Acad. Sci. USA, (Chemistry), (1993), 90, 11708.

116. M. Lebl, V. Krchñák, S. E. Salmon, K. S. Lam, Methods: A Companion to Methods in Enzymology, (1994), 6, 381.

117. K. S. Lam, Z. Zhao, S. Wade, V. Krchñák, M. Lebl, Drug Development Research, (1994), 33, 157.

118. V. Nikolaiev, A. Stierandová, V. Krchñák, B. Seligmann, K.S. Lam, S.E. Salmon, M. Lebl, Peptide Research, (1993), 6, 161.

119. M. Lebl, M. Pátek, P. Kocis, V. Krchñák, V. Hruby, S. E. Salmon, K. S. Lam, Int. J. Pept. Prot. Res., (1993), 41, 201.

120. J. Vágner, V. Krchñák, N. F. Sepetov, P. Strop, K. S. Lam, G. Barany, M. Lebl, in Innovation and Perspectives in Solid Phase Synthesis and Related Technologies (R. Epton, Ed.), Collected Papers, Third Int. Symp. Oxford, England, (1993), 347.

121. M. Lebl, V. Krchñák, N. F. Sepetov, V. Nikolaiev, A. Stierandová, P. Safar, B. Seligmann, P. Strop, K. S. Lam, S. E. Salmon, in Innovation and Perspectives in Solid Phase Synthesis and Related Technologies (R. Epton, Ed.), Collected Papers, Third Int. Symp. Oxford, England, (1993), 233.

122. M. Lebl, V. Krchñák, P. Safar, A. Stierandová, N. F. Sepetov, P. Kocis, K. S. Lam, Techniques in Protein Chemistry V, (1994), 541.

123. V. Nikolaiev, A. Stierandová, V. Krchñák, B. Seligmann, K. S. Lam, S. E. Salmon, M. Lebl, Peptide Research, (1993), 6, 161.

124. P. Kocis, V. Krchñák, M. Lebl, Tetrahedron Lett., (1993), 34, 7251.

125. S. E. Salmon, K. S. Lam, M. Lebl, A. Kandola, P. S. Khattri, S. Wade, M. Pátek, P. Kocis, V. Krchñák, D. Thorpe, S. Felder, Proc. Natl. Acad. Sci. USA, (Chemistry), (1993), 90, 11708.

126. M. Torneiro, W. C. Still, J. Am. Chem. Soc., (1995), 117, 5887.

127. H. Wennemers, W. C. Still, Tetrahedron Lett., (1994), 35, 6413.

128. R. S. Youngquist, G. R. Fuentes, M. P. Lacey, T. Keough, J. Am. Chem. Soc., (1995), 117, 3900.

129. H. Wenschuh, M. Beyermann, S. Rothemund, L. A. Carpino, M. Bienert, Tetrahedron Lett., (1995), 36, 1247.

130. J. J. Baldwin, J. J. Burbaum, I. Henderson, M. H. J. Ohlmeyer, J. Am. Chem. Soc., (1995), 117, 5589.

131. A. A. Virgilo, J. A. Ellman, J. Am. Chem. Soc., (1994), 116, 11580.

132. H. Fenniri, K. D. Janda, R. A. Lerner, Proc. Natl. Acad. Sci. USA, (Chemistry), (1995), 92, 2278.

133. F. W. Forman, I. Sucholeiki, J. Org. Chem., (1995), 60, 523.

134. G. C. Look, M. M. Murphy, D. A. Campbell, M. A. Gallop, Tetrahedron Lett., (1995), 36, 2937.

135. T. A. Rano, K. T. Chapman, Tetrahedron Lett., (1995), 36, 3789.

136. V. Krchñák, Z. Flegelová, A. S. Weichsel, M. Lebl, Tetrahedron Lett., (1995), 36, 6193.

137. B. Yan, G. Kumaravel, H. Anjaria, A. Wu, R. C. Petter, C. F. Jewell Jr., J. R. Wareing, J. Org. Chem., (1995), 60, 5736.

138. J. R. Hauske, P. Dorff, Tetrahedron Lett., (1995), 36, 1589.

139. M. Pátek, B. Drake, M. Lebl, Tetrahedron Lett., (1995), 36, 2227.

140. I, Sucholeiki, Tetrahedron Lett., (1994), 35, 7307.

141. M. Pátek, B. Drake, M. Lebl, Tetrahedron Lett., (1994), 35, 9169.

142. J. Nielsen, S. Brenner, K. D. Janda, Proceedings of the 14th American Peptide Symposium, (P. T. P. Kaumaya, R. S. Hodges, Eds.), Columbus, Ohio (1995), 92.

143. D. A. Campbell, J. C. Bermak, T. S. Burkoth, D. V. Patel, J. Am. Chem. Soc., (1995), 117, 5381.

144. M. M. Murphy, J. R. Schullek, E. M. Gordon, M. A. Gallop, J. Am. Chem. Soc., (1995), 117, 7029.

145. K. C. Nicolaou, X. Xiao, Z. Parandoosh, A. Senyei, M. P. Nova, Angew. Chem., Int. Ed. Engl. (1995), 107, 2476.

146. J. J. Burbaum, M. H. J. Ohlmeyer, J. C. Reader, I. Henderson, L. W. Dillard, G. Li, T. L. Randle, N. H. Sigal, D. Chelsky, J. J. Baldwin, Proc. Natl. Acad. Sci. USA (Pharmalogy), (1995), 92, 6027.

147. W. Karnbrock, M. Deeg, J. Gerhardt, W. Rapp, Molecular Diversity, (1998), 4, 165

148. W. Rapp, G. Nicholson, M. Maier, G. Schlotterbeck, M. Pursch, K. Albert, in Innovations and Perspectives in Solid Phase Synthesis & Combinatorial Libraries, Proceedings of the 4th International Symposium 1993, (R. Epton, Ed.), Mayflower Scientific Limited, Birmingham, (1996), 97

L 26 Polystyrene Resins

149. R. B. Merrifield, Fed. Proc., Fed. Am. Soc. Exp. Biol., (1962), 21, 412.

150. R. B. Merrifield, J. Am. Chem. Soc., (1963), 85, 2149.

151. G. R. Marshall, R. B. Merrifield, in Biochemical Aspects of Reactions on Solid Supports, Academic Press, N.Y. (1971).

152. G. Barny, R. B. Merrifield, The Peptides, Academic Press, N.Y., (1980), 2.

153. E. M. Gordon et al., J. Med. Chem., (1994), 37, 1385.

154. M. A. Gallop et al., J. Med. Chem., (1994), 37, 1233.

155. Combinatorial Peptide and Nonpeptide Libraries, a Handbook, G. Jung, Ed., VCH, Weinheim (1996).

156. L. A. Thompson and J. A. EIIman, Chem. Rev., (1996), 96, 555.

L 27 Bromo Polystyrene Resins

157. M. J. Farrall et al., J. Org. Chem., (1976), 41, 3877.

158. T. M. Fyles, C. C. Leznoff, Can. J. Chem., (1976), 54, 935.

159. J. T. Randolph et al., J. Am. Chem. Soc., (1995), 117, 5712.

160. F. X. Woolard et al., J. Org. Chem., (1997), 62, 6102.

L 28 Carboxy Polystyrene Resins

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162. C. C. Leznoff et al., Can. J. Chem., (1977), 55, 3351.

163. H. J. Meyers et al., Molecular Diversity, (1995), 1, 13.

L 29 Formyl Polystyrene Resins

164. X. Beebe et al., J. Am. Chem. Soc., (1992), 114, 10061.

165. J. M. Fréchet, C. Schuerch, J. Am. Chem. Soc., (1971), 93, 492.

166. S. W. Kaldor et al., Tetrahedron Lett., (1996), 37, 7193.

167. P. Botti et al., Peptides, Chemistry and Biology, Proceedings of the 14th American Peptide Symposium, Columbus, Ohio, U.S.A., (P. T. P. Kaumaya, R. S. Hodges, Eds.), Mayflower Scientific Ltd., England, (1996), 855.

L 30 4-Formyl-phenoxyethyl Polystyrene Resins

(4-Alkoxybenzaldehyde resin)

168. G. T. Bourne et al., J. Org. Chem., (1999), 64, 3095.

169. B. Raju et al., Tetrahedron Lett., (1997), 38, 4965.

170. S. Kobayashi et al., Tetrahedron Lett., (1998), 39, 7345.

171. C. G. Boojamra et al., J. Org. Chem., (1995), 60, 5742.

L 31 4-Formyl-3-methoxy-phenoxyethyl Polystyrene Resins

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172. A. M. Fivush, T. M. Willson, Tetrahedron Lett., (1997) 38, 7151.

173. D. Sarantakis, J. J. Bicksler, Tetrahedron Lett., (1997) 38, 7325.

174. B. Dörner et al., in Peptides 1998, Proc. 25th European Peptide Symposium, (S. Bajusz and F. Hudesz, Eds.), Budapest, Akadémiai Kiadó, (1999), 90.

175. A. Mazurov et al., Bioorg. Med. Chem. Lett., (2000), 10, 67.

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177. M. T. Bilodeau et al., J. Org. Chem., (1998), 63, 2800.

178. E. Farrant et al., Tetrahedron Lett., (2000), 41, 5383.

179. S. Caddick et al., Tetrahedron Lett., (1999), 40, 7285.

L 32 Hydroxymethyl Polystyrene Resins

180. J. M. Goldwasser et al., Can. J. Chem., (1978), 56, 1562.

181. D. J. Burdick et al., Tetrahedron Lett., (1993), 34, 2589.

182. D. R. Barn et al., Tetrahedron Lett., (1996), 37, 3213.

183. M. J. Kurth et al., J. Org. Chem., (1994), 59, 5862.

184. B. A. Dressman et al., Tetrahedron Lett., (1996), 37, 937.

L 33 Merrifield Resin

185. M. Bodanszky et al., in Peptide Synthesis, (E. Gross, J. Meienhofer, Eds.), Academic Press, Y.Wiley, New York, (1976).

186. G. Barany et al., Peptides, (1980), 2, 1.

187. B. F. Gisin, Helv. Chim. Acta, (1973), 56, 1476.

188. A. Loffet, lnt. J. Protein Res., (1971), 3, 297.

189. S. S. Wang et al., J. Org. Chem., (1975), 40, 1235.

190. M. J. Kurth et al., J. Org. Chem., (1994), 59, 5862.

191. M. V. Anuradha et al., Tetrahedron, (1995), 51, 5671.

192. J. M. Schlatter et al. (1977) Tetrahedron Lett., 18, 2851.

193. J. M. Stewart, et al., U.S. Patent 4,254,023, (1981),.

194. R. Frenette et al., Proc. Natl. Acad. Sci. USA, (1994), 90, 6906.

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196. E. Mata et al., Tetrahedron Lett., (1997), 38, 6335

L 34 Aminomethyl Polystyrene Resins

197. R. Mitchell et al., J. Org. Chem., (1978), 30, 2845.

198. W. Kornreich et al., Int. J. Peptide Protein Res., (1985), 25, 414.

199. M. Cardno, M. Bradley, Tetrahedron Lett., (1996), 37, 135.

L 35 Fmoc-2,4-dimethoxy-4'-(carboxymethoxy)-benzhydrylamine linked to Aminomethyl Polystyrene Resins

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200. H. Rink, Tetrahedron Lett., (1987), 28, 3787.

L 36 Trityl Chloride Resins

201. C. C. Leznoff, Acc. Chem. Res., (1978), 11, 327.

202. C. Chen et al., J. Am. Chem. Soc., (1994), 116, 2661.

203. K. Barlos et al., Liebigs Ann. Chem., (1988), 1079.

204. K. Barlos et al., in Peptides 1992, Proc. 22nd European Peptide Symposium, (C. H. Schneider, A. N. Eberle, Eds.), ESCOM, Leiden, (1993), 281.

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206. Z. Li, A. Ganesan, Syn. Lett., (1998), 405.

207. P. Garibay et al., Tetrahedron Lett., (1998), 39, 2207.

L 37 Chloro-(2’-chloro)trityl Polystyrene Resins

208. K. Barlos et al., Tetrahedron Lett., (1989), 30, 3943.

209. K. Barlos et al., Tetrahedron Lett., (1989), 30, 3947.

210. K. Barlos et al., Angew. Chem. Int. Ed. Engl., (1991), 30, 590.

211. K. Barlos et al., Int. J. Peptide Protein Res., (1991), 37, 513.

212. K. Barlos et al., Int. J. Peptide Protein Res., (1991), 38, 562.

213. K. Barlos et al., Int. J. Peptide Protein Res., (1991), 38, 555.

214. K. Barlos et al., Liebigs Ann. Chem., (1993), 215.

215. M. Cardno et al., J. Chem. Soc., Chem. Commun., (1995), 2163.

216. C. C. Leznoff, Acc. Chem. Res., (1978), 11, 327.

217. A. Nash et al., Tetrahedron Lett., (1996), 37, 2625.

218. W. J. Hoekstra et al., Tetrahedron Lett., (1997), 38, 2629.

219. K. Akaji, Y. Kiso, Tetrahedron Lett., (1997), 38, 5185.

220. R. E. Marti et al., Tetrahedron Lett., (1997), 38, 6145.

221. R. Bollhagen et al., J. Chem. Soc. Chem. Commun., (1994), 2559.

222. Y. Fujiwara et al., Chem. Pharm. Bull., (1994), 42, 724.

223. J. J. McNally et al., Tetrahedron Lett., (1998), 39, 967.

224. B. B. Shankar et al., Tetrahedron Lett., (1999), 39, 2447.

L 38 Polystyrene-2-Cl-Trt AA Resins

225. K. Barlos et al., Tetrahedron Lett., (1989), 30, 3943.

226. K. Barlos et al., Tetrahedron Lett., (1989), 30, 3947.

227. K. Barlos et al., Angew. Chem. Int. Ed. Engl., (1991), 30, 590.

228. K. Barlos et al., Int. J. Peptide Protein Res., (1991), 37, 513.

229. K. Barlos et al., Int. J. Peptide Protein Res., (1991), 38, 562.

230. K. Barlos et al., Int. J. Peptide Protein Res., (1991), 38, 555.

L 39 Wang Resin

231. S. W. Wang, J. Am. Chem. Soc., (1973), 95, 1328.

232. G. Lu et al., J. Org. Chem., (1981), 46, 3433.

233. B. C. Hamper et al., Tetrahedron Lett., (1996), 37, 3671.

234. C. Z. Zhang et al., Tetrahedron Lett., (1996), 37, 751.

235. Y. Wang, S. R. Wilson, Tetrahedron Lett., (1997), 38, 4021.

236. S. Hanessian, H. K. Huynh, Tetrahedron Lett., (1999), 40, 671.

L 40 HMB Linker

237. R. C. Sheppard et al., Int. J. Peptide Protein Res., (1982), 20, 451.

L 41 HMPA Linker

238. E. Atherton et al., Chem. Commun., (1978), 537, 539.

239. A. Dryland, R. C. Sheppard, J. Chem. Soc., Perkin I, (1986), 125.

L 42 Polystyrene-PHB - AA Fmoc Resins

240. S. W. Wang, J. Org. Chem., (1973), 41, 3258.

241. G. Lu et al., J. Org. Chem., (1981), 46, 3433.

242. P. Sieber, Tetrahedron Lett., (1987), 28, 6147.

L 43 REM Resins

243. R. Brown et al., J. Am. Chem. Soc., (1997), 119, 3288.

244. J. Cattney et al., Bioorg. Med. Chem. Lett., (1999), 9, 1323.

L 44 Polymeric Reagents

245. T. M. Fyles, C. C. Lenzoff, Can. J. Chem., (1975), 54, 935.

246. G. A. Crosby, N. M. Weinshenker, H. S. Uh, J. Am. Chem. Soc., (1974), 97, 2232.

247. N. M. Weinshenker, C. M. Shen, Terahedron Lett., (1972), 13, 3381.

248. W. H. Daly, Makromol. Chem. Suppl., (1979), 180, 3.

249. C. G. Overberger, K. N. Sannes, Angew. Chem., (1974), 86, 139.

250. Akelah, D.C. Sherrington, Polymer, (1983), 24, 1369.

251. E. Atherton, R. C. Sheppard, in Peptides 1974 (Y. Wolman, Ed.), Halsted Press, N.Y., (1975), 123.

L 45 Triphenylphosphine Resins

252. M. Bernard et al., J. Org. Chem., (1983), 48, 326.

253. P. Hodge et al., Chem. Commun., (1975), 633.

254. R. Caputo et al., Synthesis, (1986), 499.

255. R. Caputo et al., Synthesis, (1987), 386.

256. I. Hughes, Tetrahedron Lett., (1996), 37, 7596.

257. I.Fenger et.al., Tetrahedron Lett., (1998), 39 , 4287

L 46 Diol Resins

258. C. C. Leznoff et al., Can. J. Chem., (1973), 51, 3756.

259. S. Chamoin et al., Tetrahedron Lett., (1998), 39, 4179.

260. R. Maltais et al., Tetrahedron Lett., (2000), 41, 1691.

L 47 Bromo Acetal Resins

261. M. Patek, Lecture at Combinatorial Chemistry, London, July 11-14, (2000).

262. T. Vojkovsky et al., J. Org. Chem., (1998), 63, 3162.

L 48 Scavenger Resins

263. S. W. Kaldor et al., Tetrahedron Lett., (1996), 37, 7193.

264. J. R. Booth et al., J. Am. Chem. Soc., (1997), 119, 4882.

265. M. W. Creswell et al., Tetrahedron, (1998), 54, 3983.

266. D. L. Flynn et al., J. Am. Chem. Soc., (1997), 119, 4874.

267. M. R. Lawrence et al., Synthesis, (1997), 553.

268. M. J. Suto et al., Tetrahedron, (1998), 54, 4141.

L 49 PEG’s

269. A. Bückmann et al., Makromol. Chem., (1981), 182, 1379.

270. V. N. R. Pillai et al., J. Org. Chem., (1980), 45, 5364.

271. J. M. Harris et al., J. Polym. Sci. Polym. Chem. Edn., (1984), 22, 341.

272. S. Zalipsky et al., Eur. Polym. J., (1983), 19, 1177.

273. A. Abuchowski et al., J. Biol. Chem., (1977), 252, 3578.

274. A. Cordes et al., J. Chromat. (1986), 376, 375.

275. P. Wirth et al., Bioorg. Chem. (1991), 19, 133.

276. T. P. Kogan, Synthetic Comm. (1992), 22, 2417.

277. S. Romani et al., in Chemistry of Peptides and Proteins (W. Voelter et al., Eds.), Walter de Gruyter, Berlin, Vol. 2, (1984), 29.

278. M. Sepulchre et al., Makromol. Chem., (1983), 184, 1849.

279. I. N. Topchieva et al., Eur. Polym. J., (1988), 24, 899.

280. S. Zalipsky et al., in Peptides: Structure and Function (V. J. Hruby, K. H. Kopple, eds.), Pierce Chem. Co., Rockford, IL, (1985), 257.

281. J. M. Harris, (Ed.), Poly(ethylene glycol) Chemistry: Biotechnical and Biomedical Applications, Plenum Press, New York and London, (1992).

282. Phar. Manufacturing (2007) Issue 1, pp. 34.

L 50 Total Protected Peptide Amides

283. B. J. Backes, J. A. Ellmann, J. Am. Chem. Soc., (1994), 116, 11171.

284. C. P. Holmes et al., J. Org. Chem., (1995), 60, 2318.

285. P. Sieber, Tetrahedron Letters, (1987), 28, 2107.

L 51 Sulphonic Acid Resins

286. D. Flynn et al., J. Am. Chem. Soc., (1997), 119, 4874.

287. L. M. Gayo et al., Tetrahedron Lett., (1997), 38, 513.

288. M. Siegel et al, Tetrahedron Lett., (1997), 38, 3357.

289. A. Shuker et al, Tetrahedron Lett., (1997), 38, 6149.

290. M. R. Lawrence et al, Synthesis, (1997), 553.

291. J. Parlow et al, Tetrahedron, (1998), 54, 4013.

L 52 Chlorosulfonated Resins

292. J. Rueter et al., Tetrahedron Lett., (1998), 39, 975.

293. E. Baxter et al., Tetrahedron Lett., (1998), 39, 979.

294. H. Zhong et al., Org. Chem., (1997), 62, 9326.

295. 1. Review W. Huang et al., Chin. J. Reactive Polymers (Engl.), (1992), 1, 61.

296. J. Hunt et al., Am. Chem. Soc., (1996), 118, 9998.

297. T. Takahashi et al., Tetrahedron Lett., (1998), 39, 1369.

298. H. Zhang et al., Org. Letters., (2000), 2, 89.

299. K. Brummond et al., Tetrahedron Lett., (1999), 40, 2231.

300. M. Pirrung et al., Comb. Chem., (2000), 2, 675-680.

301. H. Hansen et al., Bioorgan med Chem Lett, (2000), 10, 2435

302. Y. Yoshida et al., Synthesis, (1999), 9, 1633-1636.

303. H. Kamogwa et al., Bull. Chem. Soc., Jpn, (1983), 56, 762.

304. Y. H. Hu et al., J. Org. Chem., (1999), 64, 1049.

305. H. Durr et al., Z. Naturforsch., B.: Chem. Sci., (1981), 36, 1149.

306. J. J. Reuter et al., Tetrahedron Lett., (1998), 39, 975.

L 53 Thiol Resins

307. S. Kobayashi et al., Tetrahedron Lett., (1996), 37, 5569.

308. S. Kobayashi et al., J. Org. Chem., (1996), 63, 4868.

309. C. L. Gibson et al., Tetrahedron Lett., (2003), 44, 1267.

L 54 Nitrophenyl carbonat Resins

310. D. Dixit et al., J. Chem. Soc., Chem Commun., (1977), 798-799.

311. D. Dixit et al., Isr. J. Chem., (1978), 17, 248-252.

312. E. Giralt et al., Tetrahedron, (1984), 40, 4141-4152.

313. B. A. Dressman et al., Tetrahedron Lett., (1996), 37, 937-940.

314. S. F. Brady et al., J. Med. Chem., (1998), 41, 401.

315. L. Yang et al., Tetrahedron Lett., (2000), 41, 6981.

316. C. Y. Ho et al., Tetrahedron Lett., (1997), 38, 2799.

317. J. R. Hauske et al., Tetrahedron Lett., (1995), 36, 1589.

318. W. Li et al., Tetrahedron Lett., (2000), 41, 6619.

319. S. His et al., Tetrahedron Lett., (2003), 44, 8581.

320. K. Park et al., Tetrahedron Lett., (2002), 43, 3899.

321. A. Paio et al., Tetrahedron Lett., (2003), 44, 1867.

322. J. Salvino et al., J. Comb. Chem., (2003), 5, 260.

323. C. Wang et al., J. Comb. Chem., (2004), 6, 899.

324. A. Ghosh et al., J. Org. Chem., (2001), 66, 2161.

325. M. Crimmins et al., Org. Lett., (2000), 2, 1065.

326. A. Smith et al., Bioorg. Med. Chem., (2000), 10, 2693.

327. M. Rabinowitz et al., Bioorg. Med. Chem., (2000), 10, 1007.

328. W. Meester et al., Tetrahedron Lett., (1999), 40, 1601.

329. L. Gouilleux et al., Tetrahedron Lett., (1996), 37, 7031.

L 55 Thioester Resins for Chemical Ligation

330. P. E. Dawson and S.B.H. Kent., Anu. Ref. Biochem., (2000), 69, 923-960.

331. P. E. Dawson et al., Science, (1994), 266, 776.

332. Review T. W. Muir et al., Methods in Enzymology (Ed. G. Fields) Academic Press, 266 ff.

333. P. E. Dawson et al., J. Am. Chem. Soc., (1997), 119, 4325.

334. S.B.H.Kent et al. Innovations and Perspectives in Solid Phase Synthesis, (Ed. R. Epton) Collected Papers of the Second International Symposium, 1991, Intercept Ltd., Andover, (1992), 1 ff

L 56 “Click”-Chemistry – PEG azides and Alkyne PEGs

335. Click Chemistry: Diverse Chemical Function form a Few Good Reactions. H. C. Kolb, M. G. Finn, and K. Barry Sharpless, Angew. Chem., Int. Eng. Ed., (2001), 40, 2004-2021.

336. The growing impact of click chemistry on drug discovery, H. C. Kolb and K. Barry Sharpless, Drug Discovery Today, (2003), 8(24), 1128-1131.

337. Cu-Catalyzed Alkyne-Azide “Click” Cycloadditions from a Mechanistic and Synthetic Perspective, V. C. Bock, H. Hiemstra and J. H. van Maarseveen, Eur. J. Org. Chem., (2006), 51-68.

338. A3-Type Star Polymer via Click Chemistry, O. Altintas, B. Yankul, G. Hizal and U. Tunca, J. Poly. Sci.: Part A, Polymer Chem., (2006), 44, 6458-6465.

339. Preparation of alumina supported copper nanoparticles and their application in the synthesis of 1, 2, 3-triazoles, M. L. Kantam, et al., J. Mol. Catal. A: Chem., (2006), 256, 273-277.

340. A Rapid and Versatile Method to Label Receptor Ligand Using “Click” Chemistry: Validation with the Muscarinic M1 Antagonist Pirenzepine, Bioconjugate Chemistry, (2006), 17, 1618-1623.

L 57 “Click”-Chemistry – Iodoacetyl PEG azides and alkynes

341. Quantitative reactivity profiling predicts functional cysteines in proteomes. E. Weerapana, C. Wang, G. M. Simon, F. Richter, S. Khare, M. B. D. Dillon, D. A. Bachovichin, K. Mowen, D. Baker, B. J. Cravatt, Nature, (2010), 468, 790-795.

L 58 TentaGel XV

342. W. Rapp et al. in Peptides 2012, Proceedings of the 32nd Peptide Symposium, (Eds. G. Kokotos, V. Constantinou-Kokotos, J. Matsoukas), European Peptide Society, (2012), 28.

343. S. Rawer et al. in Peptides 2012, Proceedings of the 32nd Peptide Symposium, (Eds. G. Kokotos, V. Constantinou-Kokotos, J. Matsoukas), European Peptide Society, (2012), 406.

L 59 Squaric Acid Polyethylene Glycols

344. C. Dingels, F. Wurm, M. Wagner, H.-A. Klok, H. Frey, Chem. Eur. J., (2012), 18, 1628.

345. U. Westerlind, A. Hobel, N. Gaidzig, E. Schmitt, H. Kunz, Angew. Chem., (2008), 120, 7662.

346. U. Westerlind, A. Hobel, N. Gaidzig, E. Schmitt, H. KunzAngew. Chem. Int. Ed., (2008), 47, 7551.

L 60 Thiol-specific PEG’ylation with Pyridyldithio PEG

347. Basic Studies on Heterobifunctional Biotin-PEG Conjugates with a 3-(4-Pyridyldithio)propionyl Marker on the second Terminus. K. Kaiser, M. Marek, T. Haselgrübler, H. Schindler, H.J. Gruber, Bioconjugate Chem., (1997), 8, 545-551.

L 61 PAL Resins

348. F. Albericio, G. Barany, Int. J. Peptide Protein Res., (1987), 30, 206.

349. M. S. Bernatowicz, S. B. Daniels, H. Köster, Tetrahedron Lett., (1989), 30, 4645.

L 62 TentaGel HMPA Resins

350. R. C. Sheppard, B. J. Williams, Int. J. Peptide Protein Res., (1982), 20, 454.

 

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