4-(Hydroxymethyl) Benzoic Acid (HMBA) on Aminomethyl Polystyrene
This resin is derived from aminomethyl polystyrene and the base labile 4-(hydroxymethyl)benzoic acid linker. It is a versatile support for the immobilization of carboxylic acids. The resulting ester bond is stable to strong acids but is cleaved by nucleophiles like amines, hydrazine or alkoxides.
Literature
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