New Resins

Trifunctional Hybrid Resins for Sequential Cleavage of Peptides

Trifunctional hybrid resins based on polystyrene or TentaGel^® matrices are designed for sequential cleavage of peptides.

The resins contain

5-10 % non-cleavable covalently attached ligands

40-45 % linker for peptide release with low concentrated TFA

40-45 % linker for peptide release with 95 % TFA

This resin type is specially suited for effective peptide library screening

Polystyrene based resins
mean particle size 75 - 150 µm (100-200 mesh)
capacity 0.25 - 0.35 mmol/g

Ordernumber	Resin	Price in €
Ordernumber	Resin	1g	5g	25g
TH 75150.02011014	PS AM AC HMPA	56.--	235.--	940.--

TentaGel^® based resins
mean particle size 90 µm
capacity 0.1 - 0.2 mmol/g

Ordernumber	Resin	Price in €
Ordernumber	Resin	1g	5g	25g
TH 30 902.011014	TentaGel AC HMPA	56.--	235.--	940.--

Trifunctional Hybrid Resins for Sequential Cleavage of Peptide Amides

Trifunctional hybrid resins based on polystyrene or TentaGel^® matrices are designed for sequential cleavage of peptide amides.

The resins contain

5-10 % non-cleavable covalently attached ligands

40-45 % linker for peptide amide release with low concentrated TFA

40-45 % linker for peptide amide release with 95 % TFA

This resin type is designed for screening of peptide amide libraries by sequential release

Polystyrene based resins
mean particle size 75 - 150 µm (100-200 mesh)
capacity 0.15 - 0.25 mmol/g

Ordernumber	Resin	Price in €
Ordernumber	Resin	1g	5g	25g
TH 75150.011014023	PS AM ac RAM	92.--	368.--	1473.--

TentaGel^® based resins
mean particle size 90 µm
capacity 0.1 - 0.2 mmol/g

Ordernumber	Resin	Price in €
Ordernumber	Resin	1g	5g	25g
TH 30 902.011014023	TentaGel ac RAM	92.--	368.--	1473.--

TOPPA - A Novel Resin for the Synthesis of Protected Peptide Amides

This resin type is based on a polystyrene or TentaGel^® matrix and combines the very acid sensitive trityl handle with the acid sensitive Rink amide handle. The peptide synthesis can be performed by standard conditions. Treatment of the TOPPA resin with diluted AcOH, TFE or mixtures of both in dichloromethane splits the trityl ester bond and cleaves off the total protected peptide amide (TOPPA). The C-terminus of the protected peptide amide is still masked by the Rink handle.

Polystyrene based resins
mean particle size 75 - 150 µm (100-200 mesh)
capacity 0.6 - 0.9 mmol/g

Ordernumber	Resin	Price in €
Ordernumber	Resin	1g	5g	25g
H 75150.033023	PS TOPPA	95.--	371.--	1483.--

TentaGel^® based resins
mean particle size 90 µm
capacity 0.18 - 0.25 mmol/g

Ordernumber	Resin	Price in €
Ordernumber	Resin	1g	5g	25g
S 30 902.012023	TentaGel TOPPA	95.--	371.--	1483.--

Resin for the Synthesis of Thioesters

Trityl mercapto acetyl Leu PAM loaded to aminomethyl Polystyrene

This resin can be used for the synthesis of peptide thioesters by Boc chemistry. After removal of the trityl protecting group by TFA/DCM treatment the first Boc amino acid is loaded to the resin by DIC/HOBt activation. Peptide synthesis follows the standard Boc synthesis protocol. After finishing the peptide synthesis, the peptide thioester resin is treated by HF resulting in the deprotected peptide thioester derivative which can be used for native chemical ligation.

Polystyrene AM PAM Leu Acetyl Mercapto Trt
mean particle size 75 - 150 µm (100-200 mesh)
capacity 0.6 - 0.9 mmol/g

Ordernumber	Resin	Price in $
		1g	5g
H 100 90	PS AM PAM Leu Acetyl Mercapto Trt	75.--	300.--

Index

New Resins

Prices in $

Prices in €

Rapp Polymere GmbH
Ernst-Simon-Str. 9
D 72072 Tübingen
Germany

Phone: xx49 7071 763157
Fax: xx49 7071 763158
E-mail: support@rapp-polymere.com

New Resins

Prices in $

Prices in €

Rapp Polymere GmbH Ernst-Simon-Str. 9 D 72072 Tübingen Germany

Phone: xx49 7071 763157 Fax: xx49 7071 763158 E-mail: support@rapp-polymere.com

Rapp Polymere GmbH
Ernst-Simon-Str. 9
D 72072 Tübingen
Germany

Phone: xx49 7071 763157
Fax: xx49 7071 763158
E-mail: support@rapp-polymere.com