Chlorotrityl Polystyrene Resins (Trityl Chloride Resin)

This highly acid labile resin is useful for the immobilization of alcohols, amines and carboxylic acids. Cleavage is in general achieved by using either 1-5% TFA in CH₂Cl₂ (containing 5% triisopropylsilane) or acetic acid.

This resin can also be used in Fmoc peptide synthesis under basic acylation conditions. Carboxylic acids can be released under very mild acidic conditions by treatment with AcOH/TFE/DCM or HFIP in DCM. Completely protected peptides are generated under this conditions.

This resin is more sensitive towards acides than the 2-chlorotrityl resins.

Literature

L 36

price: 138 $

H10031

Chlorotrityl Polystyrene

particle size: 100-200 mesh
capacity: 0.8 - 1.5 mmol/g

price: 138 $

H40031

Chlorotrityl Polystyrene

particle size: 200-400 mesh
capacity: 0.8 - 1.5 mmol/g

price: 149 $

H12516031

Chlorotrityl Polystyrene

particle size: 125 - 160 µm
capacity: 0.8 - 1.5 mmol/g

price: 149 $

H16020031

Chlorotrityl Polystyrene

particle size: 160 - 200 µm
capacity: 0.8 - 1.3 mmol/g

price: 149 $

H25031531

Chlorotrityl Polystyrene

particle size: 250 - 315 µm
capacity: 0.6 - 1.0 mmol/g

price: 149 $

H40045031

Chlorotrityl Polystyrene

particle size: 400 - 450 µm
capacity: 0.6 - 1.0 mmol/g

price: 149 $

H50056031

Chlorotrityl Polystyrene

particle size: 500 - 560 µm
capacity: 0.6 - 1.0 mmol/g

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